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  1. Sickle Cell Disease (SCD) Symptoms, Causes & Types

    Aug 13, 2025 · Sickle cell disease (SCD) is an inherited blood disorder. It causes your red blood cells to form into a “C” shape. It can cause pain and serious complications.

  2. About Sickle Cell Disease | Sickle Cell Disease (SCD) | CDC

    Feb 21, 2025 · Sickle cell disease (SCD) is a group of inherited blood disorders. Abnormal hemoglobin is produced. Red blood cells become hard and sticky and get stuck in small blood vessels, resulting …

  3. Sickle-cell disease - World Health Organization (WHO)

    Aug 6, 2025 · Sickle-cell disease (SCD) is a genetic disorder that affects haemoglobin, the molecule in red blood cells responsible for carrying oxygen. The disease causes red blood cells to become rigid …

  4. Sickle cell disease: MedlinePlus Genetics

    Sickle cell disease is a group of disorders that affects hemoglobin, the molecule in red blood cells that delivers oxygen to cells throughout the body. People with this disease have atypical hemoglobin …

  5. Sickle Cell Disease - What Is Sickle Cell Disease? | NHLBI, NIH

    Dec 10, 2025 · Sickle cell disease — also called sickle cell anemia — is a group of inherited disorders that affect hemoglobin , the major protein that carries oxygen in red blood cells. Normally, red blood …

  6. FDA Approves First Gene Therapies to Treat Patients with Sickle Cell ...

    The FDA approved the first cell-based gene therapies, Casgevy and Lyfgenia, for the treatment of sickle cell disease in patients 12 years and older.

  7. Home - SCDAA

    Since 1972, our organization has been on the forefront of improving the quality of health, life and services for individuals, families and communities affected by this rare disease and related …

  8. Sickle Cell Disease (SCD): Symptoms, Causes, and Treatment

    Sep 28, 2025 · Sickle cell disease (SCD) is an inherited blood disorder that affects red blood cells. Common symptoms include anemia, fatigue, severe pain, and swelling.

  9. Sickle Cell Disease - Johns Hopkins Medicine

    What is sickle cell disease? Sickle cell disease (SCD) is an inherited blood disorder. That means it is passed down from a parent’s genes. It causes the body to make abnormal hemoglobin. Hemoglobin …

  10. Sickle Cell Disease Fact Sheet - NHLBI, NIH

    Sickle cell disease (SCD) is the most common inherited blood disorder in the United States. In this fact sheet, learn about the causes, signs and symptoms, diagnosis, and treatment of SCD.