A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that ...

The origin of many diseases begins at the cellular level and involves multiple molecular interactions. However, previous methods have struggled to accurately observe changes in individual cells.

AGBT is also, increasingly, a showcase for instruments for spatial biology, a fast-growing field that involves pinpointing the location of RNA and protein molecules en masse. Tarbox calls the meeting ...

Explore how clinical multi-omics integration drives systems medicine, detailing data fusion methodologies and lab ...

A team led by HHMI Hanna Gray Fellow Shan Meltzer has created a detailed, cell-by-cell map of the spinal cord that offers a new framework for understanding chronic pain and provides a powerful new ...

Touch—the first sense to develop in the womb—is fundamental to our bodily experience and our everyday lives. Yet, as the least studied of the five senses, it remains somewhat mysterious at the ...

Announcing a new article publication for BIO Integration journal. Alzheimer's disease (AD) is a neurodegenerative disorder ...

The human lymphatic system is notoriously difficult to map due to its size and variability among individuals. Spatial ...

I try not to think of what would have happened if they had found this at the beginning,” says Runkel. “I find that if I just ...

This repository contains the code of the paper "DeepSpot: Leveraging Spatial Context for Enhanced Spatial Transcriptomics Prediction from H&E Images". Authors: Kalin Nonchev, Sebastian Dawo, Karina ...

Abstract: Recent advancements in spatial transcriptomics technology have enabled the capture of gene expression profiles while maintaining spatial information. Accurately identifying spatial ...

Do you want to generate spatial transcriptomics data using your H&E images? We introduce DeepSpot, a novel deep-learning model that predicts spatial transcriptomics from H&E images. DeepSpot employs a ...