TWILIGHT adopts the progressive alignment algorithm (Fig. 1c) and employs tiling strategies to band alignments (Fig. 1e). Combined with a divide-and-conquer technique (Fig. 1a), a novel heuristic ...
Abstract: Multiple Sequence Alignment (MSA) is a fundamental challenge in bioinformatics, forming the basis for addressing numerous computational biology problems, e.g., protein structure prediction ...
Abstract: Bayesian inference provides a methodology for parameter estimation and uncertainty quantification in machine learning and deep learning methods. Variational inference and Markov Chain ...