We have determined the structure, at 2.6 Šresolution, of the AML1 (Runx1) Runt domain–CBFβ–DNA ternary complex, the most common target for mutations in human leukemia. The structure reveals that the ...
The Argonautes represent a highly conserved gene family that is found in almost all eukaryotes and is even found in bacteria and archaea. Many members of the Argonaute gene family are found in the ...
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