For years, biomolecular condensates were thought to be simple, liquid-like droplets with little internal organization. New ...

RAB7A plays a central role in the final stages of autophagy, facilitating autophagosome-lysosome fusion, lysosome positioning, and cargo degradation. Its activation by guanine nucleotide exchange ...

Even after decades of peering into cells, biologists are still finding surprises. In a twist, researchers at the University of Virginia and the National Institutes of Health uncovered a new organelle, ...

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Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, ...