Pyruvate is produced by glycolysis, a process in which carbohydrates are broken down to create energy. Calcium pyruvate is a popular supplement that many people use primarily for its purported weight ...

Endogenous pyruvate is an end-product in glycolysis and a key molecule for ATP production under aerobic and anaerobic conditions, whereas exogenous pyruvate is transferred to cells via monocarboxylate ...

The tricarboxylic acid (TCA) cycle is a pivotal source for mitochondrial NADH and the core metabolic route for production of many biosynthetic precursors. Over the past 15 years, oncogenic mutations ...

The purpose of this report is to present the findings in a group of 20 patients with pulmonary insufficiency, all but 2 of whom had arterial oxygen tensions below 50 mm. of mercury. The 20 subjects ...

Image Caption: Pyruvate inhibits TNFα/NF-κB signaling and the expression of downstream pro-inflammatory genes. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles ...

Chemists have developed an organic catalyst that can drive reactions using pyruvate -- a key biomolecule in many metabolic pathways -- that are difficult and complicated to achieve using conventional ...

Low testosterone may worsen the liver-damaging effects of high-fructose diets by altering gut microbes and metabolism, a new study in mice suggests.

By converting plastic waste into a microbe-friendly food source, scientists have built an upcycling pipeline that turns the waste into a variety of useful products. The findings are detailed in the ...