Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple ...

Liver cancer in children is rare, but when it occurs, the two main types are hepatoblastoma (HB) and hepatocellular carcinoma (HCC). In some cases, however, the tumors show features of both types.

BPDCN is an aggressive type of blood cancer that originates from plasmacytoid dendritic cells (pDCs), a component of the immune system that produces type 1 interferon cytokines. These cytokines help ...

Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple brain tumor types that share a similar molecular program. Scientists at St ...

The tissue adjacent to a tumor behaves differently than areas farther away: The tumor's cancerous cells influence their surroundings, blocking the body's immune defenses and creating a sort of haven ...

Immunotherapy has revolutionized cancer treatment, yet response rates remain highly variable across tumor types and individual patients. Increasing evidence ...

A tumor marker for pancreatic cancer helps healthcare professionals detect, diagnose, or treat it. However, a person can have high tumor marker levels without having cancer. Tumor markers are ...

Cancer immunotherapies often rely on activating immune responses, yet many tumors remain resistant because their internal survival mechanisms are poorly understood.