As people age, muscles naturally lose mass and strength, a condition known as sarcopenia. The decline can make everyday activities harder and increases the risk of falls, disability and early death.

Melkani’s lab study, titled "Time-restricted feeding promotes muscle function through purine cycle and AMPK signaling in Drosophila obesity models,” was recently published in Nature Communications.

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...