NUS researchers have developed a platform that lets lab-grown muscle tissues train themselves to record-breaking strength, ...

Musculoskeletal disorders are a primary cause of disability worldwide, especially in aging societies like Japan. As ...

In work published in Nature Biotechnology, Rubin and his research group turned to 3D cell culture to take on the problem of generating sufficient satellite cells for regenerative therapies. 2 ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

We have identified a macrophage population "Mrep" that plays an essential role in muscle repair. However, in Fibrodysplasia ossificans progressiva ...

We have identified a macrophage population "Mrep" that plays an essential role in muscle repair. However, in Fibrodysplasia ...

As we age, the muscles we rely on for daily activities tend to become less reliable. With enough decline, even normal movements such as getting out of bed become risky. Low muscle mass in the ...

Mrep accumulates in damaged muscle tissue and promotes muscle regeneration by acting on muscle satellite cells through activin A. While Mrep performs beneficial functions in normal muscle repair, in ...