An AI model that screens ionizable lipids by 3D conformation identified a candidate 14.8 times more efficient than current ...

A new imaging approach is shedding light on one of cell biology’s most elusive questions: how lipids are organized and sorted within membranes.

No lipids, no life. In all organisms, lipids form cell walls, store energy and release it when necessary, and play an important role in cell signalling. It has been proved that changes in the ...

Lipids are a diverse group of organic compounds that are essential for several biological functions, ranging from energy storage to cell signaling. They are loosely described as organic, ...

Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues. A team led by ...

To create A1 lipid nanoparticles for delivering mRNA to target cells, scientists at the University of Pennsylvania used A3 coupling. A3 refers to the amine–aldehyde–alkyne coupling reaction, which the ...

The chemical industry applies lipid analysis and characterization in creating specialty chemicals and polymers. Lipids can serve as raw materials in polymer chemistry. For instance, lipid-based ...

The discovery and mass production of life-saving therapeutics and vaccines is a lot more intricate than the initial synthesis. A compound can face various complications throughout the development and ...

Penn Engineers have redesigned a key component of lipid nanoparticles (LNPs), the delivery vehicles behind mRNA vaccines, to ...