The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever, and general ...

An AI model that screens ionizable lipids by 3D conformation identified a candidate 14.8 times more efficient than current ...

Messenger RNA (mRNA) therapeutics have moved from a promising idea to clinical reality, accelerating vaccine development and opening new paths ...

LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...

Bethesda, MD – In response to the growing number of lipids expected to be discovered through lipidomics and in anticipation of the massive amounts of data that will be generated by the lipid community ...

KU Leuven Center for Cancer Biology, in collaboration with the Francis Crick Institute, has discovered how cancer cells can ...

Crenarchaeol is a large, closed-loop lipid that is present in the membranes of ammonium-oxidizing archaea. In comparison to other archaeal membrane lipids, crenarchaeol is very complex and, so far, ...

Researchers are redesigning lipid nanoparticles to do more than shuttle mRNA into cells, with preclinical studies suggesting ...