Pasca Lab specializes in growing three-dimensional organoid models from reprogrammed stem cells, which capture molecular changes during fetal brain-like development. Because the human brain cannot be ...

Age, biological sex, and human genetic factors influence the production of antibodies during the immune response. A team of scientists from the Institut Pasteur, the CNRS and the Collège de France ...

The first complete draft of the human genome was published back in 2003. Since then, researchers have worked both to improve the accuracy of human genetic data, and to expand its diversity, looking at ...

Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we evolved. But some of the most changeable regions of our DNA have been ...

Nearly 30 years ago, researchers began studying the gene Astn1, which encodes the cell adhesion protein astrotactin 1 in mice ...

Structural variants (SVs) are alterations in the DNA sequence that involve large-scale changes, typically longer than 50 base pairs. Advances in long-read sequencing have significantly increased ...

Genetic engineering is moving from the lab bench into clinics, farms, and even family planning decisions, promising to change how we prevent disease, age, and define human potential. The same tools ...

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Researchers have created a way to see your family tree as a movie rather than a still portrait by tracing where your ancestors moved across the globe over time. The statistical method can also be used ...

Scientists have cracked open some of the most mysterious corners of our DNA, revealing that parts of the human genome mutate at a far faster pace than previously imagined. By studying four generations ...