Proteins are the end products of the decoding process that starts with the information in cellular DNA. As workhorses of the cell, proteins compose structural and motor elements in the cell, and they ...

It is now relatively trivial to determine the order of amino acids in a protein. Figuring out how that order translates to a complicated three-dimensional structure that performs a specific function, ...

Proteins are important molecules—but they aren’t the only molecules in a cell, and they don’t operate alone. In a new preprint, the team behind the protein structure prediction software RoseTTAFold ...

The function of a protein is usually determined by the ligands that it binds to. The 3D structure of the binding groove or pocket can be compared to other proteins and similar residues used to make ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...