Researchers have used cryo- electron microscopy to elucidate for the first time the structure and function of a very small enzyme embedded in cell membranes. This enzyme builds complex sugar trees ...

The enzyme transhydrogenase plays a central role in regulating metabolic processes in animals and humans alike. Malfunction can lead to serious disorders. For the first time, structural biologists ...

SANTA CRUZ, CA -- Researchers at the University of California, Santa Cruz, have determined the three-dimensional structure of an RNA enzyme, or "ribozyme," that carries out a fundamental reaction ...

Biochemists have succeeded in resurrecting the ancestral genes of five detoxifying enzymes which are present in all tetrapods to show how their divergence in function has occurred. Our body produces ...

Life has evolved over billions of years, adapting to the changing environment. Similarly, enzymes—proteins that speed up biochemical reactions (catalysis) in cells—have adapted to the habitats of ...

While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...

Researchers participating in the Enzyme Function Initiative (EFI) have used a computationally rich metabolite-docking strategy to sift through a protein’s potential metabolic partners and predict its ...

Our body produces lots of enzymes that break down toxic substances. One class of such enzymes are the flavin-containing monooxygenases (FMOs), which are present in all tetrapods. Humans have five ...