EurekAlert!

First-in-class dual HIF inhibitors eliminate breast, colorectal, melanoma, and prostate tumors in mice when combined with immunotherapy

Researchers at Johns Hopkins University and the University of Maryland School of Pharmacy have developed a set of novel, ...
News Medical

University of Arkansas chemist receives $1.5 million NIH award to improve computer-aided drug design

A new $1.5 million award from the National Institutes of Health will allow a University of Arkansas chemist to develop mathematical models to improve the reliability and efficiency of computer-aided ...
EurekAlert!

Insilico Medicine delivers preclinical candidate targeting ENPP1 for cancer immunotherapy and the treatment of rare disease using generative AI

ISM5939 is being advanced as a therapy for cancer immunotherapy and the treatment of Hypophosphatasia. ISM5939 is a potentially best-in-class oral ENPP1 inhibitor with a novel molecular structure.
BioTechniques

A targeted approach to using AI in drug discovery

How are we improving the way the field of drug discovery creates machine learning algorithms to predict a protein’s interactions with a small molecule? The drug development pipeline is a costly and ...
GEN

The Growing Allure of Rational Drug Design

Structure-based approaches for drug design and virtual screening give new meaning to Louis Pasteur’s saying “Chance favors the prepared mind.” In silico methods are becoming more efficient in allowing ...