Aging men often lose the Y chromosome in a growing number of their cells—and it may be far more dangerous than once believed. This loss has been linked to heart disease, cancer, Alzheimer’s, and ...
Human cells have two copies of each chromosome, and this balance is essential for genes to be expressed in the appropriate proportions and for cells to function correctly. When errors occur during ...
Three specific genes on chromosome 21 drive widespread brain changes in Down syndrome, uncovering a new framework for potential future treatment strategies.
Two new studies of the evolutionary history of the Y chromosome show that, contrary to popular (if not scientific) belief, the male is not at risk of dying out. The Y chromosome which, among other ...
Human sex chromosomes originated from a pair of autosomes, the ordinary or non-sex chromosomes that contain the majority of our genome and come in identical pairs. That ancestral pair of autosomes ...
The complete assembly of each human chromosome is essential for understanding human biology and evolution. Using complementary long-read sequencing technologies, we complete the first linear assembly ...
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Scientists have discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make long loops in our DNA, they ...
The Stowers Institute's Workman Lab has shed new light on a novel histone acetyltransferase protein complex called ATAC. Acetyltransferases are enzymes that introduce a new acetyl functional group ...