Plerixafor (Mozobil, Sanofi, Cambridge, MA, USA) is a small molecule that reversibly disrupts the interaction of CXCR4 with its ligand SDF-1, allowing the release of SCs from the marrow. 12 It is ...

GM-CSF Knock-out CAR-T Study Published in Peer-Reviewed Journal Leukemia CRISPR/Cas9-Mediated GM-CSF knock-out (GM-CSF ko) CAR-T cells demonstrate reduced apoptosis and enhanced in vivo anti-tumor ...

In a recent study published in Jama Network, researchers investigated the impact of coronavirus disease 2019 (COVID-19) on biomarkers in the cerebrospinal fluid (CSF). Study: Viral Antigen and ...

The apolipoprotein E4 (ApoE4) allele, the strongest known genetic risk factor for late-onset sporadic Alzheimer’s disease, puts women at higher risk for the disease than men, but how remains unclear.

NEW YORK, NY—Results from a pair of small, randomized studies suggest that using granulocyte-colony stimulating factor (G-CSF) to mobilize stem cells is safe and may improve long-term cardiac function ...

Researchers have established a direct experimental link between inflammatory signals in the intestinal lining and the kind of ...

The brain's cerebrospinal fluid (CSF) pulses during deep sleep and this appears to be tied to brain wave activity and blood flow, an exploratory study showed. Large oscillations of CSF inflow to the ...

Impact of Broadening Trial Eligibility Criteria on the Inclusion of Patients With Brain Metastases in Cancer Clinical Trials: Time Series Analyses for 2012-2022 Effective diagnosis, prognostication, ...

Researchers from the MPI of Biochemistry and the Technical University of Munich have discovered new diagnostic markers for multiple sclerosis (MS), a disease that affects 3 million people worldwide.