The discovery of Hoogsteen base pairs, an alternative pairing mode to the canonical Watson–Crick structure, has significantly broadened our understanding of DNA dynamics. This conformation, in which ...

For the first time, researchers have succeeded in developing an artificial DNA base pair that is based on a different chemical force than natural genetic material. While the common natural DNA ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

There are plenty of unanswered questions about the origin of life on Earth. But the research community has largely reached consensus that one of the key steps was the emergence of an RNA molecule that ...

Uduak Thomas, Senior Editor at GEN, took a minute away from the talks, posters, and expo hall to join Julianna LeMieux, PhD, GEN’s Deputy Editor in Chief, to talk about the meeting, the sessions they ...

Study Shows How Melting Point Analysis Infers the Presence of and Identifies SNPs The melting temperature (T m) of a PCR product is dependent on both the length and sequence of the DNA. Melting curve ...

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...

Chemical structure of guanine, showing its double-ring purine structure and the functional groups involved in hydrogen bonding with cytosine. (Image: Public Domain) Guanine has the chemical formula ...

A research team at the University of Cologne has developed an artificial DNA base pair that works according to a new chemical principle. In contrast to natural bases, the novel artificial base pairs ...